Preferences for pre-exposure prophylaxis among U.S. military men who have sex with men: results of an adaptive choice based conjoint analysis study

Military Medical Research

Alex Dubov¹  Frederick L. Altice²  David Vlahov³  José I. Gutierrez⁴ 

[1] Loma Linda University, Griggs Hall 11065, 92350, Loma Linda, CA, USA;Yale School of Medicine, Section of Infectious Diseases, 135 College Street, Suite 323, 06510, New Haven, CT, USA;Department of Epidemiology-Microbial Diseases, Yale School of Public Health, 60 College St, 06510, New Haven, CT, USA;Yale School of Nursing, 400 West Campus Drive, 06477, Orange, CT, USA;Department of Epidemiology-Microbial Diseases, Yale School of Public Health, 60 College St, 06510, New Haven, CT, USA;Yale School of Nursing, 400 West Campus Drive, 06477, Orange, CT, USA;Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, 3333 California St, 94118, San Francisco, CA, USA;

关键词: Conjoint analysis;    Pre-exposure prophylaxis;    Preference;    Decision science;    HIV;    Military health;    Infectious disease;   

DOI  :  10.1186/s40779-021-00323-6

来源: Springer

【 摘 要 】

BackgroundPre-exposure prophylaxis (PrEP) prevents human immunodeficiency virus (HIV) infection, but its use remains low among U.S. military men who have sex with men (MSM), likely due to mis-matching with personal preferences. We conducted a study to characterize preferences to PrEP measures within this population.MethodsHIV-negative military MSM were recruited through a closed, Lesbian, Gay, Bisexual, and Transgendered (LGBT) military social media group. The survey was anonymous, and consisted of five experimentally varied attributes in service delivery: dosing method, provider type, visit location, lab work evaluation location, and dispensing venue. Relative importance and part-worth utility scores were generated using hierarchical bayes (HB) estimation, and the randomized first choice model was used to examine participation interest across eight possible PrEP program scenarios.ResultsA total of 429 participants completed the survey. Among the eight scenarios with varying attributes, the most preferred scenario featured a daily tablet, PrEP injection or implant, along with a military provider, smartphone/telehealth visit, and on-base locations for lab evaluation and medication pick-up. The results also emphasized the importance for providers to be familiar with PrEP prescription knowledge, and to provide interactions sensitive to sexual identity and mental health.ConclusionA PrEP program consisting of daily tablet is preferred in military healthcare settings is preferred. Long-acting implants and injections are also desired.

【 授权许可】

CC BY