Protein nanoparticles in drug delivery: animal protein, plant proteins and protein cages, albumin nanoparticles

Journal of Nanobiotechnology

Ehsan Kianfar¹ 

[1] ERNAM-Erciyes University Nanotechnology Application and Research Center, 38039, Kayseri, Turkey;Department of Analytical Chemistry, Faculty of Pharmacy, Erciyes University, 38039, Kayseri, Turkey;

关键词: Protein nanoparticles;    Drug delivery;    Animal protein;    Plant proteins;    Protein cages;    Albumin nanoparticles;   

DOI  :  10.1186/s12951-021-00896-3

来源: Springer

【 摘 要 】

In this article, we will describe the properties of albumin and its biological functions, types of sources that can be used to produce albumin nanoparticles, methods of producing albumin nanoparticles, its therapeutic applications and the importance of albumin nanoparticles in the production of pharmaceutical formulations. In view of the increasing use of Abraxane and its approval for use in the treatment of several types of cancer and during the final stages of clinical trials for other cancers, to evaluate it and compare its effectiveness with conventional non formulations of chemotherapy Paclitaxel is paid. In this article, we will examine the role and importance of animal proteins in Nano medicine and the various benefits of these biomolecules for the preparation of drug delivery carriers and the characteristics of plant protein Nano carriers and protein Nano cages and their potentials in diagnosis and treatment. Finally, the advantages and disadvantages of protein nanoparticles are mentioned, as well as the methods of production of albumin nanoparticles, its therapeutic applications and the importance of albumin nanoparticles in the production of pharmaceutical formulations.

【 授权许可】

CC BY