Advantages of intraoperative implantation of Impella 5.5 SmartAssist in the Management of Acute Post-Infarction Ventricular Septal Defect with cardiogenic shock

Journal of Cardiothoracic Surgery

Michael G. Katz¹  Shahood Fazal¹  Francis Robicsek²  Jeko M. Madjarov²  Svetozar Madzharov² 

[1] Department of Cardiology, Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, Box 1030, 1470 Madison, Ave, 10029-6574, New York, NY, USA;Sanger Heart and Vascular Institute/ Atrium Health, Charlotte, NC, USA;

关键词: Ventricular septal defect;    Impella 5.5 SmartAssist;    Acute myocardial infarction;    Cardiogenic shock;   

DOI  :  10.1186/s13019-021-01513-y

来源: Springer

【 摘 要 】

BackgroundDespite advances in surgical techniques and aggressive therapy of post-infarction ventricular septal defect (VSD) with cardiogenic shock, the overall morbidity and mortality is frustratingly high. The Impella 5.5 SmartAssist (Abiomed, Danvers, MA) is a surgically implanted temporary device, recently approved by the FDA (https://www.businesswire.com/news/home/20190925005454/en/) for treatment of patients in cardiogenic shock, and may fill a technological gap for patients who require acute circulatory support after VSD closure.Case presentationWe report our initial experience for two patients with post myocardial infarction VSD in the setting of cardiogenic shock supported with trans-aortic implantation Impella 5.5 SmartAssist. First patient had a posterior VSD with a left to right shunt (Qp/Qs ratio of 3.3), blood pressure 80/35 mmHg, right ventricle dysfunction, severe pulmonary arterial hypertension (an estimated systolic pulmonary artery pressure of 45 mmHg), and severe mitral valve regurgitation. Second patient was admitted for massive MI with large anterior VSD (Qp/Qs ratio of 2.8). Under cardiopulmonary bypass with cardioplegic arrest both patients underwent urgent VSD closure with trans-aortic implantation of the Impella. Minimal postoperative support was required. Patients were discharged on postoperative day 10 and 14 and remained well 3 months later. Follow-up echocardiogram showed no residual shunt.ConclusionsEarly surgical implantation of Impella 5.5 SmartAssist can prevent multiorgan dysfunction and stabilize the patients in cardiogenic shock with post-myocardial infarction VSD.

【 授权许可】

CC BY