Uranium contamination of milk from cattle in the uranium-mining area in Siavonga District of Zambia: a preliminary human health risk assessment

Bulletin of the National Research Centre

Kennedy Choongo¹  Gershom Chongwe²  John Yabe³  Md. Saiful Islam⁴  Titus Haakonde⁵  Gilbert Nchima⁶ 

[1] Department of Biomedical Sciences, School of Veterinary Medicine, The University of Zambia, Lusaka, Zambia;College of Agriculture, Fisheries and Forestry, School of Veterinary Science and Animal Husbandry, Fiji National University, Koronivia Campus, Suva, Fiji Islands;Department of Epidemiology and Biostatistics, School of Public Health, The University of Zambia, Lusaka, Zambia;Tropical Diseases Research Centre, Ndola, Zambia;Department of Para-clinical Studies, School of Veterinary Medicine, The University of Zambia, Lusaka, Zambia;Department of Pathobiology, Faculty of Agriculture and Natural Resources, School of Veterinary Medicine, University of Namibia, Windhoek, Namibia;Department of Soil Science, Patuakhali Science and Technology University, Patuakhali-8602, Dumki, Bangladesh;Environmental Health Section, School of Applied and Health Sciences, Evelyn Hone College of Applied Arts and Commerce, Lusaka, Zambia;Department of Para-clinical Studies, School of Veterinary Medicine, The University of Zambia, Lusaka, Zambia;Toxicology and Biochemistry Unit, Central Veterinary Research Institute, Ministry of Livestock and Fisheries, Balmoral, Chilanga, Zambia;

关键词: Cow milk;    Uranium contamination;    Health impact;    Zambia;   

DOI  :  10.1186/s42269-021-00556-4

来源: Springer

【 摘 要 】

BackgroundContamination of cow milk with uranium (U) is attracting global attention owing to U’s radio-toxicity and chemical toxicity in humans and animals. Concentrations of U in 223 cow milk samples from indigenous breeds reared in the proximity of a U mine in Zambia were measured using the inductively coupled mass spectrometry, and the human health risks from exposure to U through milk consumption were assessed.ResultsMilk from cattle reared in the U-mining area showed a significantly higher U-mean concentration (0.83 ± 0.64 µg/L; t = 9.95; tα = 0.05, p > 0.05) than milk from cattle reared in the non-mining area (0.08 µg/L ± 0.05). Among the residents of the U-mining area, the mean estimated daily intake (EDI), the target hazard quotients (THQs) and the target carcinogenic risks (TCRs) were all significantly (p < 0.05) elevated than among the residents of the non-mining area.ConclusionsSince the EDIs, THQs and TCRs and the U level in the cow milk were all within the World Health Organization’s and the United States Environmental Protection Agency’s permissible limits of 0.6 µg/kg-bw/day, < 1, < 10–4 and 30 µg/L, respectively. The current study, therefore, has insufficient evidence to implicate U exposure through consumption of cow milk in any non-carcinogenic or carcinogenic human health complications that are currently prevailing in the study area.Graphic abstract

【 授权许可】

CC BY