The functional impairment of different subtypes and occupational states in euthymic patients with bipolar disorder

BMC Psychiatry

Xingguang Luo¹  Xinyu Liu²  Yong Zhang²  Xiaojuan Ma³  Xia Sun⁴  Wenchen Wang⁴  Jian Zhang⁴ 

[1] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA;Henan Key Laboratory of Neurorestoratology, the first Affiliated Hospital of Xinxiang Medical University, Xinxiang, China;Unit of Bipolar Disorder, Tianjin Anding Hospital, 13 Liulin Road, Hexi District, 300222, Tianjin, China;Tianjin Medical College, Tianjin, China;Unit of Bipolar Disorder, Tianjin Anding Hospital, 13 Liulin Road, Hexi District, 300222, Tianjin, China;

关键词: Bipolar disorder;    Social functioning;    Neurocognitive functioning;    Employed;    Unemployed;    Subtype;   

DOI  :  10.1186/s12888-021-03242-x

来源: Springer

【 摘 要 】

BackgroundThe aim was to explore the associations between clinical symptoms, demographic variables, social and neurocognitive functioning in euthymic patients with bipolar disorder (BD) stratified by subgroups of DSM-IV BD (type I (BD-I) and type II (BD-II)) and occupational status (employed/unemployed), and to highlight the significance of occupational status when assessing social and neurocognitive functioning in euthymic BD patients.MethodsA total of 81 euthymic BD patients were participated in the study. The severity of the depressive and manic/hypomanic symptoms was measured using the 17-item Hamilton Depression Rating Scale (HDRS-17) and the Young Mania Rating Scale (YMRS), respectively. Social functioning and neurocognitive functioning were evaluated by the Functioning Assessment Short Test (FAST) and neurocognitive measures, respectively.ResultsEmployed BD patients displayed greater social functioning (autonomy, occupational functioning, interpersonal relationship domain) and better verbal learning performance and speed of processing than unemployed BD patients. The correlation between neurocognitive functioning and social functioning was stronger in the employed group than in the unemployed group. There were no significant differences in neurocognitive and social functioning between the BD-I and BD-II groups, and the correlation between neurocognitive functioning and social functioning was similar between the BD-I and BD-II groups.ConclusionEmployed BD patients may present greater occupational functioning and interpersonal relationships, as well as better verbal learning performance and speed of processing.

【 授权许可】

CC BY