Tai Chi exercise improves age‐associated decline in cerebrovascular function: a cross‐sectional study

BMC Geriatrics

Lili Li¹  Yuan He¹  Zhihua Wang²  Shun Wang³  Jiayu Wang⁴  Xinwu Cui⁴  Yinghao Chen⁵  Shaoying Guo⁵  Lixu Tang⁵  Yangqi Xing⁵  Xiongwen Ke⁵  Jingjing Wang⁵ 

[1] Central Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China;Central Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China;Department of Cardiology, Renmin Hospital of Wuhan University, 430060, Wuhan, China;Department of Cardiology, Renmin Hospital of Wuhan University, 430060, Wuhan, China;Department of Medical Ultrasound, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, 430030, Wuhan, China;School of Physical Education, Wuhan Sports University, 430079, Wuhan, China;

关键词: Ageing;    Cerebrovascular function;    Healthy ageing;    Tai Chi;   

DOI  :  10.1186/s12877-021-02196-9

来源: Springer

【 摘 要 】

BackgroundTai Chi exercise has been reported to enhance physical and mental health in the older adults; however, the mechanism remains elusive.Trial designWe recruited 289 older adults practicing Tai Chi for over 3 years, together with 277 age-matched older and 102 young adults as controls. 168 Tai Chi practitioners were successfully matched to 168 older controls aged 60–69 based on a propensity score for statistics.MethodsCerebrovascular function was evaluated by measuring the hemodynamics of the carotid artery. Spearman correlation was performed to validate the age-associated physiological parameters.ResultsCerebrovascular function in older adults significantly degenerated compared with the young, and was substantially correlated with age. Compared with the older control group, Tai Chi practitioners showed significant improvements in CVHI (cerebral vascular hemodynamics indices) Score (P = 0.002), mean blood flow velocity (P = 0.014), maximal blood flow velocity (P = 0.04) and minimum blood flow velocity (P < 0.001), whereas the age-related increases in pulse wave velocity (P = 0.022), characteristic impedance (P = 0.021) and peripheral resistance (P = 0.044) were lowered.ConclusionsThese data demonstrate a rejuvenation role of Tai Chi in improving the age-related decline of the cerebrovascular function.Trial registrationChinese Clinical Trial Registry (ChiCTR1900025187)

【 授权许可】

CC BY