Distribution of ocular biometric parameters and optimal model of anterior chamber depth regression in 28,709 adult cataract patients in China using swept‐source optical biometry

BMC Ophthalmology

Qiong Lei¹  Danmin Cao¹  Haixia Tu¹  Yong Wang²  Xi Feng³  Julio Ortega-Usobiaga⁴ 

[1] Aier Eye Hospital of Wuhan University, Wuhan, China;Aier Eye Hospital of Wuhan University, Wuhan, China;Aier School of Ophthalmology, Central South University, Changsha, China;Aier School of Ophthalmology, Central South University, Changsha, China;Department of Cataract and Refractive Surgery, Cl í nica Baviera-AIER Eye Hospital Group, Bilbao, Spain;

关键词: Axial length;    Anterior chamber depth;    Lens thickness;    Cataract;    IOLMaster 700;   

DOI  :  10.1186/s12886-021-01932-4

来源: Springer

【 摘 要 】

BackgroundThe purpose of this study was to evaluate the ocular biometric parameters in adult cataract patients from China and create an anterior chamber depth (ACD) regression model.MethodsThe ocular biometric records of 28,709 right eyes of cataract surgery candidates who were treated at Aier Eye Hospitals in nine cities from 2018 to 2019 were retrospectively analyzed. All measurements were taken with IOLMaster 700. We included patients who were at least 40 years old and were diagnosed with cataract.ResultsThe mean age of the patients was 68.6 ± 11.0 years. The mean values recorded were as follows: axial length (AL), 24.17 ± 2.47 mm; mean keratometry (Km) value, 44.26 ± 1.70 D; corneal astigmatism (CA), 1.06 ± 0.96 D; ACD, 3.02 ± 0.45 mm; lens thickness (LT), 4.52 ± 0.45 mm; central corneal thickness (CCT), 0.534 ± 0.04 mm; and white to white (WTW) corneal diameter, 11.64 ± 0.46 mm. ACD correlated positively with AL (Spearman coefficient, 0.544) and WTW (0.300), but negatively with LT (-0.660) and age (-0.285) (all P < 0.01). In the multivariate regression analysis of ACD, which included LT, AL, WTW, sex, Km, CCT, and age, there was a reasonable prediction with adjusted R2 = 0.641.ConclusionsCataract patients with longer AL and wider WTW have deeper ACD. With increasing age and lens thickening ACD becomes shallower. Based on the standardized coefficients of ACD multivariate regression analysis from the study, LT is the main factor that affects ACD, and is followed by AL.

【 授权许可】

CC BY