Gender differences in refraction prediction error of five formulas for cataract surgery

BMC Ophthalmology

Tingyang Li¹  Yibing Zhang²  Aparna Reddy²  Nambi Nallasamy³ 

[1] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA;Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, 1000 Wall St, 48105, Ann Arbor, MI, USA;Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, 1000 Wall St, 48105, Ann Arbor, MI, USA;Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA;

关键词: IOL power calculation;    Refraction prediction error;    Lens constant optimization;   

DOI  :  10.1186/s12886-021-01950-2

来源: Springer

【 摘 要 】

ObjectivesTo evaluate gender differences in optical biometry measurements and lens power calculations.MethodsEight thousand four hundred thirty-one eyes of five thousand five hundred nineteen patients who underwent cataract surgery at University of Michigan’s Kellogg Eye Center were included in this retrospective study. Data including age, gender, optical biometry, postoperative refraction, implanted intraocular lens (IOL) power, and IOL formula refraction predictions were gathered and/or calculated utilizing the Sight Outcomes Research Collaborative (SOURCE) database and analyzed.ResultsThere was a statistical difference between every optical biometry measure between genders. Despite lens constant optimization, mean signed prediction errors (SPEs) of modern IOL formulas differed significantly between genders, with predictions skewed more hyperopic for males and myopic for females for all 5 of the modern IOL formulas tested. Optimization of lens constants by gender significantly decreased prediction error for 2 of the 5 modern IOL formulas tested.ConclusionsGender was found to be an independent predictor of refraction prediction error for all 5 formulas studied. Optimization of lens constants by gender can decrease refraction prediction error for certain modern IOL formulas.

【 授权许可】

CC BY