BMC Medical Imaging | |
Rosai-Dorfman-Destombes (RDD) disease presenting as palindromic rheumatism | |
Aaron M. Goodman1  Carl K. Hoh2  Amin Haghighat Jahromi2  | |
[1] Department of Medicine, Division of Blood and Marrow Transplantation, Moores Cancer Center, University of California, San Diego, CA, USA;Department of Radiology, University of California, UCSD Medical Center, 200 W Arbor Drive, 92103-2686, San Diego, CA, USA; | |
关键词: Sinus histiocytosis with massive lymphadenopathy; Rosai-Dorfman-Destombes disease; Histiocytosis; Palindromic rheumatism; F-FDG PET/CT; | |
DOI : 10.1186/s12880-021-00596-2 | |
来源: Springer | |
【 摘 要 】
BackgroundRosai-Dorfman-Destombes (RDD) disease, is a rare proliferative and inflammatory disorder of non-Langerhans cell histiocytes.Case presentationWe report a 35-year-old woman, who originally presented with recurrent episodes of lower extremity joint/bone pain and chronic nasal stuffiness and congestion. Her worsening nasal congestion was due to an obstructing nasal cavity lesion which was subsequently biopsied. Pathology was consistent with RDD. 18F-FDG PET images demonstrated intense uptake in the paranasal sinuses and a large pelvic lymph node. Focal osseous lesions with intense 18F-FDG uptake were also observed in the lower extremity, corresponding to areas of peri-articular pain. Rheumatologic work-up was consistent with palindromic rheumatism. She was diagnosed with immune-related disseminated RDD, presenting as palindromic rheumatism.ConclusionsThis is the first case of RDD presenting as palindromic rheumatism. RDD should be considered as a possible but rare diagnosis in young patients with sinus-related symptoms and lymphadenopathy. The disease can on rare occasions be disseminated and can also present as immune-related RDD, such as in this patient.
【 授权许可】
CC BY
【 预 览 】
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RO202107036392903ZK.pdf | 2715KB | download |