Diagnostic Pathology | |
Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action | |
Amira Mohammed Ali1  Hiroshi Kunugi2  | |
[1] Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan;Department of Psychiatric Nursing and Mental Health, Faculty of Nursing, Alexandria University, Alexandria, Egypt;Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan;Department of Psychiatry, Teikyo University School of Medicine, Tokyo, Japan; | |
关键词: Hypoproteinemia; *albumin*; Blood urea nitrogen; Disease severity; Mortality; Coronavirus disease 2019; COVID-19; Multiple organ failure; Intensive care unit; Malnutrition; | |
DOI : 10.1186/s13000-021-01092-5 | |
来源: Springer | |
【 摘 要 】
Proteins represent the major building blocks of body tissues, and they regulate signaling involved in most cellular activities. Coronavirus disease 2019 (COVID-19) infection has been associated with high fatality, especially among older adults. The main cause of death is pulmonary tissue damage and multiple organ failure. The disease is associated with a hypercatabolic state that entails excessive protein loss. This review commentary sheds the light on hypoproteinemia in symptomatic/hospitalized COVID-19 with a special emphasis on its pathophysiology, screening, as well as its contribution to disease severity and adverse effects.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO202107034336429ZK.pdf | 471KB | download |