Performance of Mattis dementia rating scale-Chinese version in patients with mild cognitive impairment and Alzheimer’s disease

BMC Neurology

Qihao Guo¹  Keliang Chen²  Shuxia Qian³  Qiaobing Guan³ 

[1] Department of Gerontology, Shanghai Jiao Tong University Affiliated Six People’s Hospital, Shanghai, China;Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China;Department of Neurology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China;

关键词: Alzheimer’s disease;    Mild cognitive impairment;    Mattis dementia rating scale;   

DOI  :  10.1186/s12883-021-02173-0

来源: Springer

【 摘 要 】

BackgroundTo identify the applicability of the Chinese Version of Mattis Dementia Rating Scale (DRS-CV).MethodsThe DRS-CV was administered to 483 participants, including 136 normal controls, 167 patients with mild cognition impairment (MCI), and 180 patients with Alzheimer’s disease (AD). Receiver Operating Characteristic (ROC) curve was used to evaluate the sensitivity and specificity of the scale.ResultsThe scores of DRS-CV were ranked in the order of NC > MCI > mild AD > moderate AD group. Memory was the sensitive function affected at a relatively earlier stage of AD. ROC curve analysis indicated the DRS-CV total score and memory subscale showed excellent sensitivity and specificity in the discrimination between MCI from mild AD and mild AD from moderate AD, but poor sensitivity and specificity in the discrimination between MCI and NC.ConclusionThe DRS-CV is useful to the early diagnosis and severity of AD, not to the early identification of MCI.

【 授权许可】

CC BY