The Maudsley model of anorexia nervosa treatment for adolescents and young adults (MANTRa): a study protocol for a multi-center cohort study

Journal of Eating Disorders

Stefanie Truttmann¹  Julia Philipp¹  Leonie Kahlenberg¹  Sonja Werneck-Rohrer¹  Andreas F. K. Karwautz¹  Tanja Wittek¹  Michael Zeiler¹  Petra Sackl-Pammer¹  Gudrun Wagner¹  Susanne Ohmann¹  Dunja Mairhofer¹  Gabriele Schöfbeck¹  Ellen Auer-Welsbach²  Ulrike Schmidt³  Doris Koubek⁴ 

[1] Department of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria;Department of Neurology and Psychiatry of Childhood and Adolescence, Clinical Center Klagenfurt, 9020, Klagenfurt am Wörthersee, Austria;Institute of Psychiatry, Psychology & Neuroscience, King’s College London, WC2R 21S, London, UK;Medical Practice for Child and Adolescent Psychiatry, 4020, Linz, Austria;

关键词: MANTRa;    Maudsley model;    Anorexia nervosa;    Treatment;    Psychotherapy;    Adolescents;    Young adults;    Study protocol;   

DOI  :  10.1186/s40337-021-00387-8

来源: Springer

【 摘 要 】

BackgroundThe treatment of anorexia nervosa (AN) is often challenging due to medical complications as well as high relapse and mortality rates. Studies about effective treatment options for people with AN are particularly scarce in the adolescent population. This paper is a study protocol for a multi-center cohort study assessing the feasibility, acceptability and efficacy of a new, manualized treatment program, the “Maudsley Model of Anorexia Nervosa Treatment for Adolescents and Young Adults” (MANTRa) compared to psychotherapeutic treatment as usual (TAU).Methods/designOne hundred patients between 13 and 21 years who meet the inclusion criteria will receive 24 to 34 individual weekly MANTRa therapy sessions or weekly TAU sessions. Primary outcome variables will be BMI and eating disorder psychopathology 12 months after baseline. Further changes in central coherence, cognitive flexibility, emotion recognition, comorbid psychopathology (e.g. depression, obsessive-compulsive and anxiety disorders, non-suicidal self-injury), personality factors and therapeutic alliance will be assessed.DiscussionThis multi-center study will examine the utility of the treatment program MANTRa for adolescents with AN and, therefore enhances the current knowledge about potential treatments for this patient group.Trial registrationClinicalTrials.gov Identifier: NCT03535714. Registered: 24/05/2018 (retrospectively registered, still recruiting).

【 授权许可】

CC BY