Effects of management of infection source of echinococcosis in Linzhi, Tibet Autonomous Region of China

Infectious Diseases of Poverty

Bing-Cheng Ma¹  Ying Wang²  Li-Ying Wang³  Hua-Sheng Pang⁴  Gongsang Quzhen⁴ 

[1] Linzhi Center for Disease Control and Prevention, 850000, Linzhi, China;National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Center for Tropical Diseases; National Center for International Research on Tropical Diseases, MOST; Key Laboratory of Parasite and Vector Biology, MOH, 200025, Shanghai, China;National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Center for Tropical Diseases; National Center for International Research on Tropical Diseases, MOST; Key Laboratory of Parasite and Vector Biology, MOH, 200025, Shanghai, China;Doctorate School of Chemical and Biological Sciences for Health (CBS2), University of Montpellier, 34395, Montpellier, France;Tibet Center for Disease Control and Prevention, Key Laboratory of Echinococcosis Prevention and Control, National Health Commission, 850000, Lhasa, China;

关键词: Echinococcosis;    Dog management;    Dog infection;    Linzhi;    China;   

DOI  :  10.1186/s40249-021-00805-8

来源: Springer

【 摘 要 】

BackgroundEchinococcosis is highly endemic in western and northern China. Tibet Autonomous Region (TAR) is the most serious prevalent area. Linzhi is located in southeastern part of TAR. Dogs are the primary infection source for the transmission of echinococcosis to humans. A control and prevention campaign based on dog management has been implemented in the past three years. This study aims to evaluate the effects of dog management on the infection rate of dogs.MethodsData of dog population, registration and de-worming of seven counties/district in Linzhi between 2017 and 2019 were obtained from the annual prevention and control report. Domestic dog fecal samples were collected from each endemic town of seven counties/district in Linzhi in 2019 to determine the infection of domestic dogs using coproantigen enzyme-linked immunosorbent assay (ELISA). Data analysis was processed using SPSS statistics to compare dog infection rate between 2016 and 2019 by chi-square test, and maps were mapped using ArcGIS.ResultsIn Linzhi, domestic dog population has decreased from 17 407 in 2017 to 12 663 in 2019, while the registration rate has increased from 75.9% in 2017 to 98.6% in 2019. Similarly, stray dog population has decreased from 14 336 in 2017 to 11 837 in 2019, while sheltered rate has increased from 84.6% in 2017 to 96.6% in 2019. Dog de-worming frequency has increased from 4 times per annum in 2017 to 12 times in 2019, indicating that approximately every dog was dewormed monthly. A total of 2715 dog fecal samples were collected for coproantigen ELISA assay. The dog infection rate was 2.8% (77/2715) in 2019, which was significantly lower than 7.3% (45/618) in 2016 (P < 0.05).ConclusionsIncreased dog registration, decreased dog population, and increased dog de-worming frequency contributed to significantly decrease the dog infection rate in Linzhi. Control and prevention campaign based on dog management could significantly decrease dog infection with Echinococcus spp. in echinococcosis endemic areas.

【 授权许可】

CC BY