Unintended changes in ocular biometric parameters during a 6-month follow-up period after FS-LASIK and SMILE

Eye and Vision

Si Cao¹  Hechen Li¹  Rong Zhu¹  Songan Wu¹  Fangjun Bao²  Junjie Wang²  Qinmei Wang²  Xiaobo Zheng²  Riccardo Vinciguerra³  Bernardo T. Lopes⁴  Ahmed Elsheikh⁵ 

[1] Eye Hospital, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China;Eye Hospital, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China;The Institution of Ocular Biomechanics, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China;Humanitas San Pio X Hospital, Milan, Italy;School of Engineering, University of Liverpool, L69 3GH, Liverpool, UK;School of Engineering, University of Liverpool, L69 3GH, Liverpool, UK;National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK;Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China;

关键词: Posterior corneal surface;    Internal anterior chamber depth;    The length from corneal endothelium to retina;    FS-LASIK;    SMILE;   

DOI  :  10.1186/s40662-021-00232-8

来源: Springer

【 摘 要 】

BackgroundCorneal refractive surgery has become reliable for correcting refractive errors, but it can induce unintended ocular changes that alter refractive outcomes. This study is to evaluate the unintended changes in ocular biometric parameters over a 6-month follow-up period after femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE).Methods156 consecutive myopic patients scheduled for FS-LASIK and SMILE were included in this study. Central corneal thickness (CCT), mean curvature of the corneal posterior surface (Kpm), internal anterior chamber depth (IACD) and the length from corneal endothelium to retina (ER) were evaluated before and after surgery over a 6-month period.ResultsBoth the FS-LASIK and SMILE groups (closely matched at the pre-surgery stage) experienced flatter Kpm, shallower IACD and decreased ER 1 week post-surgery (P < 0.01), and these changes were larger in FS-LASIK than in SMILE group. During the 1 week to 6 months follow up period, Kpm, IACD and ER remained stable unlike CCT which increased significantly (P < 0.05), more in the FS-LASIK group.ConclusionsDuring the follow up, the posterior corneal surface became flatter and shifted posteriorly, the anterior chamber depth and the length from the corneal endothelium to retina decreased significantly compared with the pre-surgery stage. These unintended changes in ocular biometric parameters were greater in patients undergoing FS-LASIK than SMILE. The changes present clear challenges for IOL power calculations and should be considered to avoid affecting the outcome of cataract surgery.

【 授权许可】

CC BY