Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside

Clinical Epigenetics

Markus List¹  Jan Baumbach²  Kimberly Glass³  Edwin K. Silverman⁴  Giuditta Benincasa⁵  Claudio Napoli⁶  Paola Paci⁷  Cinzia Marchese⁸  Paolo Parini⁹  Bradley A. Maron^1,10  Joseph Loscalzo^1,10  Enrico Petrillo^1,11  Fortunato Ciardiello^1,12  Lucia Altucci^1,12  Federica Sarno^1,12  Antonella Verrienti^1,13  Albert-Lazlo Barabasi^1,14  Sebastiano Filetti^1,15 

[1] Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany;Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany;Department of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark;Chair of Computational Systems Biology, University of Hamburg, Notkestrasse 9, Hamburg, Germany;Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania “Luigi Vanvitelli”, Naples, Italy;Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania “Luigi Vanvitelli”, Naples, Italy;Clinical Department of Internal Medicine and Specialistic Units, AOU, University of Campania “Luigi Vanvitelli”, Naples, Italy;Department of Computer, Control, and Management Engineering, Sapienza University, Rome, Italy;Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy;Department of Laboratory Medicine and Department of Medicine, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden;Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Department of General Internal Medicine and Primary Care, Brigham and Women’s Hospital, Boston, MA, USA;Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Napoli, Italy;Department of Translational and Precision Medicine, Sapienza University, Rome, Italy;Network Science Institute and Department of Physics, Northeastern University, Boston, MA, USA;Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Department of Network and Data Science, Central European University, Budapest, Hungary;School of Health, Unitelma Sapienza University, Rome, Italy;

关键词: Epigenetics;    Cancer;    CVD;    Precision medicine;    Network medicine;    Algorithms;    Epi-drugs;   

DOI  :  10.1186/s13148-021-01047-z

来源: Springer

【 授权许可】

CC BY