Natural bio-based monomers for biomedical applications: a review

Biomaterials Research

Won-Gun Koh¹  Haejin Joo²  Mallinath S. Birajdar²  Hansoo Park² 

[1] Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea;Department of Integrative Engineering, Chung-Ang University, Seoul, Republic of Korea;

关键词: Natural bio-based monomers;    Itaconic acid;    Succinic acid;    Citric acid;    Hyaluronic acid;    Glutamic acid;   

DOI  :  10.1186/s40824-021-00208-8

来源: Springer

【 摘 要 】

In recent years, synthetic and semi-synthetic polymer materials have been widely used in various applications. Especially concerning biomedical applications, their biocompatibility, biodegradability, and non-toxicity have increased the interest of researchers to discover and develop new products for the well-being of humanity. Among the synthetic and semi-synthetic materials, the use of natural bio-based monomeric materials presents a possible novel avenue for the development of new biocompatible, biodegradable, and non-toxic products. The purpose of this article is to review the information on the role of natural bio-based monomers in biomedical applications. Increased eco-friendliness, biocompatibility, biodegradability, non-toxicity, and intrinsic biological activity are some of the attributes which make itaconic, succinic, citric, hyaluronic, and glutamic acids suitable potential materials for biomedical applications. Herein, we summarize the most recent advances in the field over the past ten years and specifically highlight new and interesting discoveries in biomedical applications.Graphical abstractNatural origin acid-based bio-monomers for biomedical applications

【 授权许可】

CC BY