Synergistic Activation of Antitumor Immunity by a Particulate Therapeutic Vaccine

Advanced Science

Zheng Li¹  Feng Li¹  Junhua Mai²  Kenji Yokoi²  Haoran Liu²  Xuewu Liu²  Maricela Ramirez²  Xiaojun Xia³  Haifa Shen⁴  Jianliang Shen⁵  Jun Li⁶  Zhaoqi Li⁶  Jingxin Zhang⁶  Mauro Ferrari⁷  Elizabeth A. Mittendorf⁸ 

[1] Center for Bioenergetics, Houston Methodist Academic Institute, Houston, TX, 77030, USA;Department of Nanomedicine, Houston Methodist Academic Institute, Houston, TX, 77030, USA;Department of Nanomedicine, Houston Methodist Academic Institute, Houston, TX, 77030, USA;Department of Experimental Medicine, Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, 510060, China;Department of Nanomedicine, Houston Methodist Academic Institute, Houston, TX, 77030, USA;Houston Methodist Cancer Center, Houston, TX, 77030, USA;Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, 10065, USA;Department of Nanomedicine, Houston Methodist Academic Institute, Houston, TX, 77030, USA;School of Ophthalmology & Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou, 325035, China;Department of Nanomedicine, Houston Methodist Academic Institute, Houston, TX, 77030, USA;Xiangya Hospital of Central South University, Changsha, Hunan, 410000, China;Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, 98195, USA;Department of Surgery, Brigham and Women's Hospital, Boston, MA, 02115, USA;Breast Oncology Program, Dana‐Farber/Brigham and Women's Cancer Center, Boston, MA, 02115, USA;

关键词: antigen peptides;    cancer;    innate immunity;    microparticles;    nanoparticles;    therapeutic vaccines;   

DOI  :  10.1002/advs.202100166

来源: Wiley

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