Clonazepam-induced lichenoid drug eruption: a case report

BMC Psychiatry

Jung-Im Na¹  Hee Won Yang²  Jong Bin Bae³  Ki Woong Kim⁴ 

[1] Department of Dermatology, Seoul National University Bundang Hospital, Seongnam, South Korea;Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea;Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea;Department of Psychiatry, Seoul National University, College of Medicine, Seoul, South Korea;Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea;Department of Psychiatry, Seoul National University, College of Medicine, Seoul, South Korea;Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, South Korea;

关键词: Clonazepam;    Cutaneous;    Lichenoid;    Drug eruption;   

DOI  :  10.1186/s12888-021-03132-2

来源: Springer

【 摘 要 】

BackgroundLichenoid drug eruption is rare and can mimic idiopathic lichen planus and other dermatoses. Clonazepam, a commonly used drug for the treatment of anxiety-related disorders and seizures, is known to be an unlikely cause of cutaneous adverse effects. Only one case report of LDE due to clonazepam has been reported.Case presentationA 81-year-old male patient with Alzheimer’s disease developed a lichenoid eruption after taking clonazepam. He developed a violaceous scaly patch on his lower extremities, from both buttocks to the feet. The cutaneous eruption resolved 2 months after cessation of clonazepam and with initiation of corticosteroid therapy.ConclusionA skin eruption that develops after clonazepam administration can be a lichenoid drug eruption, which is less likely to resolve spontaneously and requires discontinuation of clonazepam administration.

【 授权许可】

CC BY