Muscle weakness, functional capacities and recovery for COVID-19 ICU survivors

BMC Anesthesiology

Pauline Smondack¹  Yann Combret²  Tristan Bonnevie³  Francis-Edouard Gravier³  Clément Medrinal⁴  Guillaume Prieur⁵  Bouchra Lamia⁶  Guillaume Fossat⁷  Emmanuelle Desmalles⁷  Denys Mayard⁷ 

[1] ADIR Association, Bois-Guillaume, France;Intensive Care Unit Department, Groupe Hospitalier du Havre, Avenue Pierre Mendes France, 76290, Montivilliers, France;Research and Clinical Experimentation Institute (IREC), Pulmonology, ORL and Dermatology, Louvain Catholic University, 1200, Brussels, Belgium;Normandie Univ, UNIROUEN, EA3830-GRHV, 76 000, Rouen, France;Institute for Research and Innovation in Biomedicine (IRIB), 76 000, Rouen, France;ADIR Association, Bois-Guillaume, France;Normandie Univ, UNIROUEN, EA3830-GRHV, 76 000, Rouen, France;Institute for Research and Innovation in Biomedicine (IRIB), 76 000, Rouen, France;Intensive Care Unit Department, Groupe Hospitalier du Havre, Avenue Pierre Mendes France, 76290, Montivilliers, France;IFMK Saint Michel, 75015, Paris, France;Normandie Univ, UNIROUEN, EA3830-GRHV, 76 000, Rouen, France;Institute for Research and Innovation in Biomedicine (IRIB), 76 000, Rouen, France;Intensive Care Unit Department, Groupe Hospitalier du Havre, Avenue Pierre Mendes France, 76290, Montivilliers, France;Research and Clinical Experimentation Institute (IREC), Pulmonology, ORL and Dermatology, Louvain Catholic University, 1200, Brussels, Belgium;Normandie Univ, UNIROUEN, EA3830-GRHV, 76 000, Rouen, France;Institute for Research and Innovation in Biomedicine (IRIB), 76 000, Rouen, France;Pulmonology Department, Groupe Hospitalier du Havre, Avenue Pierre Mendes France, 76290, Montivilliers, France;Pulmonology, Respiratory Department, Rouen University Hospital, Rouen, France;Service de Médecine Intensive Réanimation, Centre Hospitalier Régional d’Orléans, Orléans, France;

关键词: COVID-19;    Intensive care unit;    Mechanical ventilation;    Muscle weakness;    Physiotherapy;   

DOI  :  10.1186/s12871-021-01274-0

来源: Springer

【 摘 要 】

BackgroundFew studies have evaluated muscle strength in COVID-19 ICU survivors. We aimed to report the incidence of limb and respiratory muscle weakness in COVID-19 ICU survivors.MethodWe performed a cross sectional study in two ICU tertiary Hospital Settings. COVID-19 ICU survivors were screened and respiratory and limb muscle strength were measured at the time of extubation. An ICU mobility scale was performed at ICU discharge and walking capacity was self-evaluated by patients 30 days after weaning from mechanical ventilation.ResultsTwenty-three patients were included. Sixteen (69%) had limb muscle weakness and 6 (26%) had overlap limb and respiratory muscle weakness. Amount of physiotherapy was not associated with muscle strength. 44% of patients with limb weakness were unable to walk 100 m 30 days after weaning.ConclusionThe large majority of COVID-19 ICU survivors developed ICU acquired limb muscle weakness. 44% of patients with limb weakness still had severely limited function one-month post weaning.

【 授权许可】

CC BY