Chronic administration of plasma from exercised rats to sedentary rats does not induce redox and metabolic adaptations

The journal of physiological sciences

article

Georgios Goutianos¹  Nikos V. Margaritelis¹  Theodora Sparopoulou¹  Aristidis S. Veskoukis¹  Ioannis S. Vrabas¹  Vassilis Paschalis⁵  Michalis G. Nikolaidis¹  Antonios Kyparos¹ 

[1] Department of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki;Intensive Care Unit, 424 General Military Hospital of Thessaloniki;Department of Animal Structure and Function, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki;Department of Biochemistry and Biotechnology, University of Thessaly;School of Physical Education and Sport Science, National and Kapodistrian University of Athens

关键词: Adaptations;    Exercise;    Muscle;    Plasma injection;    Rats;    Redox;   

DOI  :  10.1186/s12576-020-00737-2

来源: Springer

【 摘 要 】

The present study aimed to investigate whether endurance exercise-induced changes in blood plasma composition may lead to adaptations in erythrocytes, skeletal muscle and liver. Forty sedentary rats were randomly distributed into two groups: a group that was injected with pooled plasma from rats that swam until exhaustion and a group that was injected with the pooled plasma from resting rats (intravenous administration at a dose of 2 mL/kg body weight for 21 days). Total antioxidant capacity, malondialdehyde and protein carbonyls were higher in the plasma collected from the exercised rats compared to the plasma from the resting rats. Νo significant difference was found in blood and tissue redox biomarkers and in tissue metabolic markers between rats that received the “exercised” or the “non-exercised” plasma (P > 0.05). Our results demonstrate that plasma injections from exercised rats to sedentary rats do not induce redox or metabolic adaptations in erythrocytes, skeletal muscle and liver.

【 授权许可】

Unknown