Hydroxychloroquine and Covid-19: A Cellular and Molecular Biology Based Update

Indian journal of clinical biochemistry

article

Amit Pal¹  Anil Pawar²  Kalyan Goswami¹  Praveen Sharma¹  Rajendra Prasad³ 

[1] Department of Biochemistry, AIIMS;Department of Zoology, DAV University;Department of Biochemistry, MM Institute of Medical Sciences and Research

关键词: Covid-19 Hydroxychloroquine Cytokine storm Severe acute respiratory syndrome coronavirus 2 In;   

DOI  :  10.1007/s12291-020-00900-x

来源: Springer

【 摘 要 】

As the time for finding a definitive and safe cure as a vaccine for novel Corona Virus Disease 2019 (Covid-19) is still far, there is need to study in depth about the other potential drugs, which can save millions of lives due to Covid-19 pandemic. Right at the center of the debate is the use of drug “Hydroxychloroquine” as a prophylaxis as well as a treatment strategy against Covid-19 in conjunction with azithromycin. In this review, we will study the cellular and molecular aspects of hydroxychloroquine, which had driven its use in Covid-19 patients, as well as its chemistry and pharmacokinetics along with clinical trials going on worldwide using hydroxychloroquine against Covid-19.

【 授权许可】

Unknown