Gait analysis of patients with knee osteoarthritis highlights a pathological mechanical pathway and provides a basis for therapeutic interventions

EFORT Open Reviews

article

Julien Favre¹  Brigitte M. Jolles² 

[1] Swiss BioMotion Laboratory, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne;Swiss BioMotion Laboratory, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Switzerland；Institute of Microengineering

关键词: knee;    osteoarthritis;    gait analysis;    ambulatory mechanics;    adduction moment;    flexion moment;    flexion angle;   

DOI  :  10.1302/2058-5241.1.000051

学科分类：神经科学

来源: The British Editorial Society of Bone & Joint Surgery

【 摘 要 】

Osteoarthritis (OA), the most common type of arthritis, is a disease causing pain, deformity, and dysfunction of the joints. This condition affects a constantly increasing portion of the population, inducing serious socio-economic concerns worldwide. Costs related to OA in the USA were estimated have already exceeded $330 billion in 2003,1 and numbers are expected to rise with the growth of obesity and the ageing of the population to the point of becoming the fourth leading cause of disability by 2020 and affecting a third of the population by 2030.2,3 The knee is the most frequently affected load-bearing joint, with disease developing more often in the medial than in any other knee compartment. An important element contributing to the burden of knee OA is the absence of a cure. Current therapeutic options consist primarily of medication and rehabilitation to reduce symptoms, and of arthroplasty later in the disease, when the joint becomes too severely damaged. Consequently, there is a critical need to enhance therapeutic options, which requires the improvement of our understanding of OA pathogenesis.

【 授权许可】

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