Prevention of infection in primary THA and TKA

EFORT Open Reviews

article

Philip F. Dobson¹  Michael R. Reed² 

[1] Royal Victoria Infirmary;Wansbeck Hospital

关键词: arthroplasty;    hip;    infection;    knee;    surgical site infection (SSI);   

DOI  :  10.1302/2058-5241.5.200004

学科分类：神经科学

来源: The British Editorial Society of Bone & Joint Surgery

【 摘 要 】

The publication of Joseph Lister’s ‘Antiseptic principle in the practice of surgery’ in 1867 revolutionized surgical practice.1 Despite his critics at the time, the routine use of antiseptic skin preparation for everything from venepuncture to major surgery became universally accepted as a method for reducing infection rates. The development of antibiotics and their use in surgical prophylaxis in many branches of surgical practice has also become commonplace, and has further reduced infection. Despite the ongoing evolution and refinement of surgical practice, surgical site infection (SSI) remains a risk for every patient, including those undergoing primary total hip and knee arthroplasty procedures, and is associated with a three-fold mortality rate at one year. The overall incidence of SSI following primary total hip arthroplasty (THA) is between 0.2% and 2.2%2 and rates of deep or peri-prosthetic joint infection (PJI) in THA and primary total knee arthroplasty (TKA) range between 0.3% and 1.9%,3 and up to 10% in revision cases.4 The risk of SSI and PJI is related to surgical factors and patient factors such as age, body mass index (BMI), co-morbidities, and lifestyle.5 Significant morbidity is associated with this devastating complication, the economic burden on our healthcare system is considerable , and the personal cost to the affected patient is immeasurable.6–8 This article is not an exhaustive list on infection prevention, but will discuss more recent tactics in modern orthopaedic practice to reduce infection rates in primary THA and TKA surgery.

【 授权许可】

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