Frontiers in non-union research

EFORT Open Reviews

article

Enrique Gómez-Barrena¹  Norma G. Padilla-Eguiluz²  Philippe Rosset³ 

[1] Hospital La Paz-IdiPAZ, Universidad Autónoma de Madrid;Université de Tours;Hospital de Traumatología, Hospital Universitario La Paz

关键词: ATMPs (advanced therapy medicinal products);    bone healing;    cell therapy;    MSCs (mesenchymal stromal cells) and biomaterials;    non-union;   

DOI  :  10.1302/2058-5241.5.190062

学科分类：神经科学

来源: The British Editorial Society of Bone & Joint Surgery

【 摘 要 】

Non-union or pseudarthrosis represents the inability of bone to heal after a fracture. Although this is a general definition that is well accepted by most orthopaedic trauma surgeons, it is not a simple concept. The absence of timely bone healing after a fracture, during the expected consolidation process, is associated with the presence of specific signs that confirm that the fracture will not spontaneously heal and therefore may require specific actions to obtain the desired bone healing. As surveys among specialists clearly show, both the consolidated bone fracture and the absence of consolidation producing a non-union or pseudarthrosis both deserve more precise definitions.

【 授权许可】

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