A Projection Argument for Differential Inclusions, with Applications to Persistence of Mass-Action Kinetics

Symmetry Integrability and Geometry-Methods and Applications

article

Manoj Gopalkrishnan¹  Ezra Miller²  Anne Shiu³ 

[1] School of Technology and Computer Science, Tata Institute of Fundamental Research;Department of Mathematics, Duke University;Department of Mathematics, University of Chicago, 5734 S. University Avenue

关键词: dif ferential inclusion;    mass-action kinetics;    reaction network;    persistence;    global attractor conjecture;   

DOI  :  10.3842/SIGMA.2013.025

来源: National Academy of Science of Ukraine

【 摘 要 】

Motivated by questions in mass-action kinetics, we introduce the notion of vertexical family of differential inclusions. Defined on open hypercubes, these families are characterized by particular good behavior under projection maps. The motivating examples are certain families of reaction networks – including reversible, weakly reversible, endotactic, and strongly endotactic reaction networks – that give rise to vertexical families of mass-action differential inclusions. We prove that vertexical families are amenable to structural induction. Consequently, a trajectory of a vertexical family approaches the boundary if and only if either the trajectory approaches a vertex of the hypercube, or a trajectory in a lower-dimensional member of the family approaches the boundary. With this technology, we make progress on the global attractor conjecture, a central open problem concerning mass-action kinetics systems. Additionally, we phrase mass-action kinetics as a functor on reaction networks with variable rates.

【 授权许可】

Unknown