Multi-Round compared to Real-Time Delphi for consensus in core outcome set (COS) development: a randomised trial

Trials

Mandy Daly¹  Shireen Meher²  Jamie J. Kirkham³  Patricia Healy⁴  Linda Biesty⁵  Elaine Ní Bhraonáin⁶  Fiona A. Quirke⁷  Tim Hurley⁸  Declan Devane⁹  David M. Haas^1,10  Frank H. Bloomfield^1,11  Eleanor J. Molloy^1,12  Karen Walker^1,13 

[1] Advocacy and Policymaking, Irish Neonatal Health Alliance, Wicklow, Ireland;Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK;Centre for Biostatistics, University of Manchester, Manchester, UK;College of Medicine, Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland;School of Nursing and Midwifery, National University of Ireland Galway, Galway, Ireland;College of Medicine, Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland;School of Nursing and Midwifery, National University of Ireland Galway, Galway, Ireland;Qualitative Research in Trials Centre (QUESTS), National University of Ireland Galway, Galway, Ireland;Family Support Liaison, Irish Neonatal Health Alliance, Wicklow, Ireland;Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Galway, Ireland;Health Research Board – Trials Methodology Research Network (HRB-TMRN), Galway, Ireland;College of Medicine, Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland;Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Galway, Ireland;Paediatrics and Child Health, Trinity College Dublin, Dublin, Ireland;Health Research Board – Trials Methodology Research Network (HRB-TMRN), Galway, Ireland;College of Medicine, Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland;School of Nursing and Midwifery, National University of Ireland Galway, Galway, Ireland;Evidence Synthesis Ireland, National University of Ireland Galway, Galway, Ireland;Cochrane Ireland, National University of Ireland Galway, Galway, Ireland;Indiana University School of Medicine Department of Obstetrics and Gynecology, Indianapolis, USA;Liggins Institute, University of Auckland, Auckland, New Zealand;Paediatrics and Child Health, Trinity College Dublin, Dublin, Ireland;Department of Neonatology, Children’s Hospital Ireland at Crumlin and Tallaght, Coombe Women and Infants University Hospital, Dublin, Ireland;RPA Newborn Care, Sydney Local Health District, Sydney, Australia;

关键词: Real-Time Delphi;    Multi-Round Delphi;    Core outcome sets;    Methodology;    Randomised trial;   

DOI  :  10.1186/s13063-021-05074-2

来源: Springer

【 摘 要 】

BackgroundThe Delphi method is used in a wide variety of settings as a method of building consensus on important issues. Traditionally, the Delphi method uses multiple rounds of a survey to allow for feedback of other participants’ survey responses in between rounds. By informing participants about how others answer a question or prioritise specific topics, it allows for diverse opinions to inform the consensus process. For this reason, the Delphi method is popular as a consensus building approach in developing core outcome sets (COS), i.e. the minimum agreed set of standardised outcomes that should be measured and reported in studies on a specific health condition. In a COS setting, participants prioritise the importance of outcomes for inclusion in a COS. This usually involves participating in multiple rounds of a survey that can span several weeks or months. Challenges with participant retention have been highlighted in previous COS. We will compare a three-round with a Real-Time Delphi approach on prioritised outcomes. This trial is embedded within the COHESION study which is developing a COS for interventions treating neonatal encephalopathy.MethodsOne hundred and eighty stakeholders (parents/caregivers of infants diagnosed and treated with neonatal encephalopathy, healthcare providers and researchers) will be randomised using stratified randomisation to take part in either the Multi-Round or Real-Time Delphi. Stakeholders will rate the importance of the same set of outcomes in both arms. We will compare the prioritised outcomes at the end of both surveys as well as other parameters such as feedback, initial condition and iteration effects.DiscussionThis trial will provide evidence to inform decisions on the use of Multi-Round compared to Real-Time Delphi survey methods.Trial registrationNCT04471103. Registered on 14 July 2020.

【 授权许可】

CC BY