Uncovering a ‘sensitive window’ of multisensory and motor neuroplasticity in the cerebrum and cerebellum of male and female starlings

eLife

Jasmien Orije¹  Emilie Cardon¹  Elisabeth Jonckers¹  Annemie Van der Linden¹  Marleen Verhoye¹  Julie Hamaide¹  Veerle M Darras² 

[1] Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium;Laboratory of Comparative Endocrinology, Biology Department, Leuven, Belgium;

关键词: European starling;    neuroplasticity;    sexual dimorphism;    diffusion tensor imaging;    birdsong;    cerebellum;    Sturnus vulgaris;    Other;   

DOI  :  10.7554/eLife.66777

来源: eLife Sciences Publications, Ltd

【 摘 要 】

Traditionally, research unraveling seasonal neuroplasticity in songbirds has focused on the male song control system and testosterone. We longitudinally monitored the song behavior and neuroplasticity in male and female starlings during multiple photoperiods using Diffusion Tensor and Fixel-Based techniques. These exploratory data-driven whole-brain methods resulted in a population-based tractogram confirming microstructural sexual dimorphisms in the song control system. Furthermore, male brains showed hemispheric asymmetries in the pallium, whereas females had higher interhemispheric connectivity, which could not be attributed to brain size differences. Only females with large brains sing but differ from males in their song behavior by showing involvement of the hippocampus. Both sexes experienced multisensory neuroplasticity in the song control, auditory and visual system, and cerebellum, mainly during the photosensitive period. This period with low gonadal hormone levels might represent a ‘sensitive window’ during which different sensory and motor systems in the cerebrum and cerebellum can be seasonally re-shaped in both sexes.

【 授权许可】

CC BY