Investigation of association of genetic variant rs3918242 of matrix metalloproteinase-9 with hypertension, myocardial infarction and progression of ventricular dysfunction in Irish Caucasian patients with diabetes: a report from the STOP-HF follow-up programme

BMC Cardiovascular Disorders

J. Paul Spiers¹  Max Waterstone¹  Joseph Gallagher²  Mark Ledwidge²  Kenneth McDonald²  Chris Watson³  Cristin Ryan⁴  John Gilmer⁴  Adam Russell-Hallinan⁵ 

[1] Department of Pharmacology and Therapeutics, Trinity College Dublin, Dublin, Ireland;STOP-HF Unit, St. Vincent’s University Healthcare Group, Dublin, Ireland;School of Medicine, University College Dublin, Dublin, Ireland;STOP-HF Unit, St. Vincent’s University Healthcare Group, Dublin, Ireland;Wellcome-Wolfson Institute for Experimental Medicine, Queen’s University, Belfast, Northern Ireland;School of Medicine, University College Dublin, Dublin, Ireland;School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland;Wellcome-Wolfson Institute for Experimental Medicine, Queen’s University, Belfast, Northern Ireland;

关键词: MMP-9;    Diabetes;    Hypertension;    Myocardial infarction;    Imaging;    Heart failure;    Prevention;    Genetics;    Single nucleotide polymorphism;   

DOI  :  10.1186/s12872-021-01860-7

来源: Springer

【 授权许可】

CC BY