Computational design of highly stable and soluble alcohol dehydrogenase for NADPH regeneration

Bioresources and Bioprocessing

Haisheng Zhou¹  Ziyuan Wang²  Jinling Xu²  Tong Deng²  Lirong Yang³  Hongyu Zhang³  Haoran Yu³  Jianping Wu³ 

[1]Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, 310027, Hangzhou, China

[2]Institute of Bioengineering, College of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, China

[3]Institute of Bioengineering, College of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, China

[4]Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, 310027, Hangzhou, China

关键词: Alcohol dehydrogenase;    Computational design;    Soluble expression;    NADPH regeneration;    Chiral alcohols;   

DOI  :  10.1186/s40643-021-00362-w

来源: Springer

【 授权许可】

CC BY