Antimicrobial Resistance & Infection Control | |
Effects of coronavirus disease 2019 (COVID-19) pandemic on antimicrobial prevalence and prescribing in a tertiary hospital in Singapore | |
David C. Lye1 Tau Hong Lee1 Tat Ming Ng2 Hui Lin Tay2 Boon Hou Chua2 Sock Hoon Tan2 Shi Thong Heng2 Min Yi Yap2 Christine B. Teng3 | |
[1] Department of Infectious Diseases, National Centre for Infectious Diseases, Singapore, Singapore;Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore;Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore;Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore;Department of Pharmacy, Tan Tock Seng Hospital, Singapore, Singapore;Department of Pharmacy, Tan Tock Seng Hospital, Singapore, Singapore;Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore; | |
关键词: COVID-19; Antimicrobial prevalence; Singapore; Resources; Antimicrobial stewardship; Pandemic; | |
DOI : 10.1186/s13756-021-00898-8 | |
来源: Springer | |
【 摘 要 】
BackgroundThe deployment of antimicrobial stewardship (AMS) teams to deal with the COVID-19 pandemic can lead to a loss of developed frameworks, best practices and leadership resulting in adverse impact on antimicrobial prescribing and resistance. We aim to investigate effects of reduction in AMS resources during the COVID-19 pandemic on antimicrobial prescribing.MethodsOne of 5 full-time equivalent AMS pharmacists was deployed to support pandemic work and AMS rounds with infectious disease physicians were reduced from 5 to 2 times a week. A survey in acute inpatients was conducted using the Global Point Prevalence Survey methodology in July 2020 and compared with those in 2015 and 2017–2019.ResultsThe prevalence of antimicrobial prescribing (55% in 2015 to 49% in 2019 and 47% in 2020, p = 0.02) and antibacterials (54% in 2015 to 45% in 2019 and 42% in 2020, p < 0.01) have been reducing despite the pandemic. Antimicrobial prescribing in infectious disease wards with suspected or confirmed COVID-19 cases was 29% in 2020. Overall, antimicrobial prescribing quality indicators continued to improve (e.g. reasons in notes, 91% in 2015 to 94% in 2019 and 97% in 2020, p < 0.01) or remained stable (compliance to guideline, 71% in 2015 to 62% in 2019 and 73% in 2020, p = 0.08).ConclusionDuring the COVID-19 pandemic, there was no increase in antimicrobial prescribing and no significant differences in antimicrobial prescribing quality indicators.
【 授权许可】
CC BY
【 预 览 】
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RO202106281076638ZK.pdf | 898KB | download |