The efficacy of repetitive transcranial magnetic stimulation in treating patients with chronic daily headache

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Amira A. Labib¹  Ann Ali AbdElkader¹  Ayat Allah Farouk Ahmad¹  Leqaa Ali El-Mekkawy¹  Ebtesam Mohammed Fahmy²  Shaimaa shaheen Mohammed Abd El Razek² 

[1] Clinical Neurophysiology Unit, Faculty of Medicine, Cairo University, Cairo, Egypt;Department of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt;

关键词: Repetitive trans-cranial magnetic stimulation;    Chronic daily headache;    Tension headache;    Migraine;   

DOI  :  10.1186/s41983-021-00278-4

来源: Springer

【 摘 要 】

BackgroundHeadache is the most common pain disorder, affecting around 66% of the global population. This study aimed to investigate the efficacy of high-frequency repetitive transcranial magnetic stimulation (rTMS) in treating patients with primary chronic daily headaches (chronic tension-type headache and chronic migraine).MethodsTwenty-seven patients participated in the study, divided into 2 groups: a study group (16 patients) and a control group (11 patients). Treatment consisted of 12 high-frequency (5 Hz) real rTMS sessions, delivered over the left dorsolateral prefrontal cortex (DLPFC), whereas sham rTMS was used for the control group.ResultsPatients of the study group, after real rTMS stimulation, showed a high statistically significant reduction of the measured headache parameters compared to the control group (P value < 0.001), and the percentage of improvement was 94.5%. No significant reduction of headache parameters, after sham rTMS stimulation, was observed in the control group (P value > 0.05) and the percentage of improvement was 7.9%.ConclusionHigh-frequency rTMS is effective in reducing chronic tension headaches and chronic migraines. This finding runs with the approval of the suggested role of DLPFC in pain control. This might open opinions for new treatment strategies in tension-type headache and migraine prevention.

【 授权许可】

CC BY