DDIT3 Directs a Dual Mechanism to Balance Glycolysis and Oxidative Phosphorylation during Glutamine Deprivation

Advanced Science

Jingtong Li¹  Qingyuan Zhang¹  Ronghua Shi²  Mingyue Li²  Lianxin Liu²  Mian Wu³  Rick Francis Thorne⁴  Xu Dong Zhang⁴  Jingmin Li⁵ 

[1] Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150081, China;Heifei National Laboratory for Physical Sciences at the Microscale of USTC, CAS Centre for Excellence in Molecular Cell Science, the First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, 230027, China;Heifei National Laboratory for Physical Sciences at the Microscale of USTC, CAS Centre for Excellence in Molecular Cell Science, the First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, 230027, China;Translational Research Institute, Henan Provincial People's Hospital, School of Clinical Medicine, Henan University, Zhengzhou, Henan, 450003, China;Translational Research Institute, Henan Provincial People's Hospital, School of Clinical Medicine, Henan University, Zhengzhou, Henan, 450003, China;Translational Research Institute, Henan Provincial People's Hospital, School of Clinical Medicine, Henan University, Zhengzhou, Henan, 450003, China;Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150081, China;

关键词: COQ9;    COX4;    DDIT3/CHOP;    electron transfer chain;    glutamine deprivation;    glycolysis;   

DOI  :  10.1002/advs.202003732

来源: Wiley

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