Single human oocyte transcriptome analysis reveals distinct maturation stage‐dependent pathways impacted by age

Aging Cell

Sara Ruiz¹  Marc Elosua‐Bayes¹  Patricia Lorden¹  Paula Nieto¹  Holger Heyn¹  Anna Mallol²  Sílvia Llonch²  Bernhard Payer³  Rita Vassena⁴  Montserrat Barragán⁴  Filippo Zambelli⁴ 

[1] CNAG‐CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain;Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain;Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain;Universitat Pompeu Fabra (UPF), Barcelona, Spain;Clínica EUGIN, Barcelona, Spain;

关键词: advanced maternal age;    ageing;    assisted reproduction;    BMI;    fertility;    human oocyte;    single‐cell RNA‐Seq;    transcriptomics;   

DOI  :  10.1111/acel.13360

来源: Wiley

【 授权许可】

CC BY