A novel swine model of the acute respiratory distress syndrome using clinically relevant injury exposures

Physiological Reports

Brendan M. McCracken¹  Carmen I. Colmenero¹  Mohamad H. Tiba¹  Danielle C. Leander¹  Kevin R. Ward²  J. Scott VanEpps³  Rodney C. Daniels⁴  Thomas L. Flott⁵  Kristine E. Konopka⁶  Kathleen A. Stringer⁷  Robert P. Dickson⁸  Michael W. Sjoding⁹  Jean A. Nemzek^1,10 

[1] Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA;Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA;Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA;Department of Pediatrics, Pediatric Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Department of Pathology, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA;Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA;Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA;Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA;Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA;Unit of Laboratory Animal Medicine, University of Michigan, Ann Arbor, MI, USA;

关键词: acute lung injury;    acute respiratory distress syndrome;    critical care;    diffuse alveolar damage;    direct lung injury;    indirect lung injury;    porcine models;    sepsis;    septic shock;   

DOI  :  10.14814/phy2.14871

来源: Wiley

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