Chemogenetic activation of central gastrin‐releasing peptide‐expressing neurons elicits itch‐related scratching behavior in male and female mice

Pharmacology Research & Perspectives

Yohji Fukazawa¹  Daisuke Uta²  Ayano Saika³  Fumihiro Saika³  Tomoe Y. Nakamura³  Norikazu Kiguchi⁴  Mei‐Chuan Ko⁵  Shiroh Kishioka⁶ 

[1] Department of Anatomy, Kansai University of Health Sciences, Sennan‐gun, Osaka, Japan;Department of Applied Pharmacology, Faculty of Pharmaceutical Sciences, University of Toyama, Toyama City, Toyama, Japan;Department of Pharmacology, Wakayama Medical University, Wakayama City, Wakayama, Japan;Department of Pharmacology, Wakayama Medical University, Wakayama City, Wakayama, Japan;Department of Physiological Sciences, School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama City, Wakayama, Japan;Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston‐Salem, NC, USA;Faculty of Wakayama Health Care Sciences, Takarazuka University of Medical and Health Care, Wakayama City, Wakayama, Japan;

关键词: dorsal horn;    DREADD;    GRP;    GRPR;    pruritus;    sex;    spinal cord;   

DOI  :  10.1002/prp2.790

来源: Wiley

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