Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau

EMBO Molecular Medicine

Geidy E Serrano¹  Eric M Reiman¹  Thomas G Beach²  Ruben Smith³  Shorena Janelidze³  Niklas Mattsson‐Carlgren⁴  Oskar Hansson⁵  Erik Stomrud⁶  Sebastian Palmqvist⁶  Randall J Bateman⁷  Jeffrey L Dage⁸ 

[1] Banner Alzheimer’s Institute, Phoenix, AZ, USA;Banner Sun Health Research Institute, Sun City, AZ, USA;Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden;Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden;Department of Neurology, Skåne University Hospital, Lund University, Lund, Sweden;Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden;Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden;Department of Neurology, Washington University School of Medicine, Saint‐Louis, MO, USA;Memory Clinic, Skåne University Hospital, Malmö, Sweden;Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden;Memory Clinic, Skåne University Hospital, Malmö, Sweden;Department of Neurology, Washington University School of Medicine, Saint‐Louis, MO, USA;Eli Lilly and Company, Indianapolis, IN, USA;

关键词: Alzheimer’s disease;    amyloid;    phosphorylated tau;    plasma;    tau;   

DOI  :  10.15252/emmm.202114022

来源: Wiley

【 授权许可】

CC BY