A collagen extraction and deuterium oxide stable isotope tracer method for the quantification of bone collagen synthesis rates in vivo

Physiological Reports

Philip J. Atherton¹  Daniel J. Wilkinson¹  Kenneth Smith¹  Matthew S. Brook¹  Steven L. Britton²  Heikki Kainulainen³  Sanna Lensu³  Lauren G. Koch⁴  Kirsty J. Elliott‐Sale⁵  Rita Civil⁵  Craig Sale⁵  Ian Varley⁵  Lívia Santos⁵ 

[1] Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital, Derby, UK;Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA;Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA;Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland;Department of Physiology and Pharmacology, The University of Toledo, Toledo, OH, USA;Musculoskeletal Physiology Research Group, Sport Health and Performance Enhancement Research Centre, School of Science and Technology, Nottingham Trent University, Nottingham, UK;

关键词: bone turnover;    collagen synthesis;    deuterium oxide;    pyrolysis;    stable isotopes;   

DOI  :  10.14814/phy2.14799

来源: Wiley

【 授权许可】

CC BY