Peptide location fingerprinting reveals modification‐associated biomarker candidates of ageing in human tissue proteomes

Aging Cell

Alexander Eckersley¹  Michael J. Sherratt¹  Matiss Ozols¹  Ronan O'Cualain²  Stacey Warwood²  David Knight²  Venkatesh Mallikarjun³  Joe Swift³  Kieran T. Mellody⁴  Rachel E. B. Watson⁵  Christopher E. M. Griffiths⁵ 

[1] Division of Cell Matrix Biology & Regenerative Medicine, The University of Manchester, Manchester, UK;Division of Cell Matrix Biology & Regenerative Medicine, The University of Manchester, Manchester, UK;Biological Mass Spectrometry Core Research Facility, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK;Division of Cell Matrix Biology & Regenerative Medicine, The University of Manchester, Manchester, UK;Wellcome Centre for Cell‐Matrix Research, The University of Manchester, Manchester, UK;Division of Musculoskeletal & Dermatological Sciences, The University of Manchester, Manchester, UK;Division of Musculoskeletal & Dermatological Sciences, The University of Manchester, Manchester, UK;NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK;

关键词: ageing;    biomarkers;    mass spectrometry;    peptide location fingerprinting;    photoageing;    proteomics;    skin;    tendon;   

DOI  :  10.1111/acel.13355

来源: Wiley

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