NR4A1 knockdown confers hepatoprotection against ischaemia‐reperfusion injury by suppressing TGFβ1 via inhibition of CYR61/NF‐κB in mouse hepatocytes

Journal of Cellular and Molecular Medicine

Baofei Jiang¹  Kun Wu¹  Shaochuang Wang²  Long Ma³  Chengming Zhou⁴  Jun Cao⁴  Ting Xu⁵ 

[1] Department of General surgery, The Affiliated Huai’an No. 1 People’s Hospital of Nanjing Medical University, Huai’an, China;Department of Hepatobiliary Surgery, The Affiliated Huai’an No. 1 People’s Hospital of Nanjing Medical University, Huai’an, China;Department of Intensive Care Unit, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China;Department of hepatic and Laparoscopic Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China;The Affiliated Huai’an No. 1 People’s Hospital of Nanjing Medical University, Huai’an, China;The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China;

关键词: cysteine‐rich angiogenic inducer 61;    hepatic injury;    ischaemia‐reperfusion;    nuclear receptor subfamily 4;    group A;    member 1;    nuclear‐factor kappa B;    transforming growth factor β1;   

DOI  :  10.1111/jcmm.16493

来源: Wiley

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