High Frequency Deep Brain Stimulation of Superior Cerebellar Peduncles in a Patient with Cerebral Palsy

Tremor and Other Hyperkinetic Movements

article

Suzhen Lin¹  Chencheng Zhang²  Hongxia Li¹  Yuhan Wang²  Yunhao Wu²  Tao Wang²  Yixin Pan²  Bomin Sun²  Yiwen Wu¹  Dianyou Li² 

[1] Department of Neurology and Institute of Neurology, Ruijin Hospital, affiliated with Shanghai Jiaotong University School of Medicine;Department of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, affiliated with Shanghai Jiaotong University School of Medicine

关键词: Superior cerebellar peduncles;    deep brain stimulation;    dystonia;    cerebral palsy;    cerebellum;   

DOI  :  10.5334/tohm.551

学科分类：社会科学、人文和艺术（综合）

来源: Ubiquity Press

【 摘 要 】

Background: Globus pallidus internus (GPi) deep brain stimulation (DBS) is widely used in patients with isolated dystonia; however, its use remains controversial in patients with acquired dystonia and cerebral palsy. Case presentation: We report the first case of a cerebral palsy patient, who failed to recover 2 years after GPi DBS; DBS was administered on both superior cerebellar peduncles (SCPs) and dentate nuclei (DNs). The monopolar stimulation results suggested that DBS was better administered via the SCPs than via the DNs. At six months follow-up, the patient exhibited a significant improvement of dystonia and spasticity, as well as in her quality of life. Discussion: SCP DBS may be a potential treatment for cerebral palsy patients with dystonia and spasticity who do not respond well to GPi DBS.

【 授权许可】

CC BY