Sensorimotor Integration and GABA-ergic Activity in Embouchure Dystonia: An Assessment with Magnetoencephalography

Tremor and Other Hyperkinetic Movements

article

Bisena Bulica¹  Christos Sidiropoulos²  Abhimanyu Mahajan³  Andrew Zillgitt⁴  Patricia Kaminski¹  Susan M. Bowyer¹ 

[1] Department of Neurology, Henry Ford Hospital;Department of Neurology and Ophthalmology, Michigan State University;Division of Movement Disorders, Department of Neurology, University of Cincinnati;Department of Neurology, Beaumont Neuroscience Center, Royal Oak

关键词: Embouchure dystonia;    MEG;    sensorimotor integration;    magnetoencephalography;    coherence source imaging;    MEG-CSI;   

DOI  :  10.5334/tohm.487

学科分类：社会科学、人文和艺术（综合）

来源: Ubiquity Press

【 摘 要 】

Background: Embouchure dystonia (ED) is a task-specific dystonia affecting musicians thought to be related to alteration in sensorimotor processing and loss of cortical inhibition. Case Report: Magnetoencephalography-coherence source imaging (MEG-CSI) was used to map connectivity between brain regions by imaging neuronal oscillations that are coherent across the brain in patient with ED at rest and while using the index finger to evoke dystonia normally triggered by playing the flute. Discussion: During rest, there was increased coherence in the bilateral frontal and parietal regions that became more focal during dystonia. Diffuse hyperexcitability and increased coherence persisted in bilateral parietal regions as well as the bilateral frontal regions.

【 授权许可】

CC BY