Self-Injurious Behaviour in SCA17: A New Clinical Observation

Tremor and Other Hyperkinetic Movements

article

Roberta Bonomo¹  Anna Latorre¹  Kailash P Bhatia¹ 

[1] Department of Clinical and Movement Neurosciences, University College London (UCL) Institute of Neurology;Department “G.F. Ingrassia”, Section of Neurosciences, University of Catania;Department of Human Neurosciences, Sapienza University of Rome

关键词: SCA17;    self-injury;    neurotransmitters;    serotonin;    dopamine;   

DOI  :  10.5334/tohm.478

学科分类：社会科学、人文和艺术（综合）

来源: Ubiquity Press

【 摘 要 】

Background: Self-injurious behaviour has historically been associated with borderline personality disorder. Nevertheless, over recent years, it has been reported in numerous neurological syndromes, especially hyperkinesias. Case report: Two cases of SCA17 manifested self-injurious behaviour, namely repetitive scratching of the skin resulting in severe excoriations. In one of them, the abnormal behaviour was associated with the inability to resist the impulse to commit the act along with relief following the damage. Discussion: This is the first report describing self-injurious behaviour in SCA17, but the mechanisms underlying it are still not clear. Further studies are needed to clarify the pathophysiology of such manifestation in hyperkinetic syndromes.

【 授权许可】

CC BY