Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome

Tremor and Other Hyperkinetic Movements

article

Norma L. Alvarado-Franco¹  Catalina Gonzalez-Marques²  Leticia A. Olguín-Ramírez¹  Alejandro Garza-Alpirez¹  Giovana Femat-Roldan¹  Daniel Martinez-Ramirez¹ 

[1] Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud;Department of Emergency Medicine, College of Medicine, University of Florida;Neurocenter

关键词: Autoimmune disorders;    Sjögren syndrome;    neuroimmunology;    chorea;    athetosis;   

DOI  :  10.5334/tohm.419

学科分类：社会科学、人文和艺术（综合）

来源: Ubiquity Press

【 摘 要 】

Background: Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by exocrine gland and extraglandular symptoms. We present a case report of pSS with an initial presentation of athetoid movements. Case Report: A 74-year-old female presented with a 2-month history of slow undulating movements in her trunk and thighs that eventually spread to her neck and lower extremities. She also reported dry eyes, dry mouth, as well as pain in her shoulders and thighs. Her proinflammatory markers and rheumatologic profile were positive. Her salivary gland biopsy revealed a Focus score > 2. Brain magnetic resonance imaging was normal. A diagnosis of pSS was made. The patient’s symptoms improved with hydroxychloroquine, pilocarpine, gabapentin, and clonazepam. Discussion: Clinicians should consider and screen for primary autoimmune disorders as a cause of subacute athetoid movements in elderly patients. Although aggressive treatment has been recommended, treatment should be tailored to each patient’s specific needs.

【 授权许可】

CC BY