Further Evidence for Celiac Disease-associated Chorea?

Tremor and Other Hyperkinetic Movements

article

Ruth H. Walker¹ 

[1] Departments of Neurology, James J. Peters Veterans Affairs Medical Center;Mount Sinai School of Medicine

关键词: Chorea;    celiac disease;    anti-gliadin antibodies;    gluten sensitivity;   

DOI  :  10.5334/tohm.80

学科分类：社会科学、人文和艺术（综合）

来源: Ubiquity Press

【 摘 要 】

Background: A number of neurological conditions have been reported to be associated with gluten sensitivity, including ataxia, peripheral neuropathy, epilepsy, and occasionally, chorea. The pathogenic role of anti-gliadin antibodies has been questioned, and pathophysiology remains controversial. Case Report: I report chorea in a patient with celiac disease, which responded to a gluten-restricted diet. The response of the movement disorder to change in diet strongly suggests a functional role for anti-gliadin antibodies in the generation of chorea, probably involving basal ganglia targets. Discussion: Gluten sensitivity may be a treatable cause of chorea.

【 授权许可】

CC BY