Substance Abuse Profiles of Patients Admitted to the Alcohol and Drug Addiction Research, Treatment, and Education Center in Turkey

Turkish Journal of Pharmaceutical Sciences

article

Fadime CANBOLAT¹  Aykut KUL¹  Murat ÖZDEMİR¹  Uğur ATİK¹  Ahmet AYDIN²  S. Tuncel ÖZDEN¹  K. Nevzat TARHAN¹ 

[1] Üsküdar University, Advanced Toxicology Analysis Laboratory;Yeditepe University, Faculty of Pharmacy, Department of Toxicology

关键词: Mass spectrometer;    substance abuse;    urine;    statistical assessment;   

DOI  :  10.4274/tjps.50470

来源: Galenos Yayinevi

【 摘 要 】

Objectives: To determine the substance abuse profiles of patients treated a Drug Addiction Research, Treatment, and Education Center (AMATEM) in association with the percentage of substance use distribution and multiple substance use in their urine samples. For this, we retrospectively evaluated the urine sample analysis reports of 600 male and female patients aged 13 to 65 years who were treated at the AMATEM unit of İstanbul Neuropsychiatry Hospital between January 1st, 2015, and December 12th, 2015. Materials and Methods: The urine samples were sent to Üsküdar University Advanced Toxicology Analysis Laboratory and were analyzed using a UPLC tandem mass spectrometer (UPLC-MS/MS). To determine the substance use profiles of the patients applying to AMATEM, statistical assessment was performed on the analysis reports of the patients. Results: When the analysis reports of the 600 urine samples were examined, 293 patients were identified to have used addictive substances. The substances most frequently detected in the urine samples were respectively: cannabis, alcohol, morphine, cocaine, synthetic cannabinoids, 3,4-Methylenedioxymethamphetamine, and amphetamine. Conclusion: The findings in our study resemble the rates of cannabis use by the young population throughout the world. Our results show differences to the literature regarding the consumption of synthetic cannabinoids because the variety of synthetic cannabinoids change rapidly around the world each year.

【 授权许可】

Unknown