Is hemoglobin the missing link in the pathogenesis of COVID-19?

Anaesthesia, Pain & Intensive Care

ARTICLE

AmerMajeed¹  Matloob Ashraf Shajar¹ 

[1] King Faisal Specialist Hospital and Research Centre

关键词: Corona virus disease;    COVID-19;    SARS-CoV-2;    ARDS;    Hemoglobin;   

DOI  :  10.35975/apic.v24i1.1216

学科分类：社会科学、人文和艺术（综合）

来源: THK

【 摘 要 】

This editorial considers studies which establish our current understanding of SARSCoV-2 and the indicated direction for treatment of COVID-19 patients and future research. Recent modelling studies point to the effect of SARS-CoV-2 on hemoglobin as a key element in understanding the pathogenesis of COVID-19. This would suggest that the focus of treatment of COVID-19 would need to shift towards maintaining the oxygen carrying capacity of blood; potentially with blood transfusions and superoxygenation, perhaps including hyperbaric oxygen therapy. Further, early prevention of thromboembolism, and suppression of the immune response due to hemoglobin damage, may help contain the clinical course.

【 授权许可】

CC BY-NC