Phytochemical and antimicrobial evaluation of selected medicinal plants in Meru community of Kenya

Journal of Medicinal Plants for Economic Development

ARTICLE

Jackson K. Mutembei¹  Patrick G. Kareru¹  Edwin S. Madivoli¹  Martin K. Murigi¹  Joseph Karanja¹  Kipyegon Cheruiyot²  Sylvester O. Rechab¹  Ernest G. Maina¹ 

[1] Department of Chemistry, Jomo Kenyatta University of Agriculture and Technology;Department of Zoology, Jomo Kenyatta University of Agriculture and Technology;Department of Physical Sciences, University of Kabianga

关键词: Antimicrobial evaluation;    phytochemical profile;    medicinal plants;    Disc agar diffusion;    bacterial strain;   

DOI  :  10.4102/jomped.v2i1.44

学科分类：自然科学（综合）

来源: AOSIS

【 摘 要 】

Background:  Increased resistance against antimicrobial medication used to combat bacterial infection necessitates the need for alternative medication.   Objective:  This study seeks to evaluate the antimicrobial potential and phytochemical profiles of 10 medicinal plants collected from Chuka, Tharaka-Nithi County of Kenya. Plant samples were collected, dried, pulverised into fine powders and extracted with distilled water.   Methodology:  Qualitative phytochemical screening and disc-agar diffusion methods were used according to standard method to determine phytochemical profile and antimicrobial activity of the aqueous extracts against four bacterial strains and a fungus.   Results:  Phytochemical investigation revealed the presence of terpenoids, tannins and reducing sugars in all the plants except one. Saponins were found to be present in  Albizia anthelmintica, Entada leptostachya, Raponae rhododendroides  and  Warbugia ugandensis . Steroids were present in seven plants while alkaloids were present in five.  Albizia anthelmintica, E. leptostachya  and  W. ugandensis  extracts were active against  Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli  and  Candida albicans. Escherichia coli  was the most susceptible bacteria against all the plant extracts tested, except  Harrisonia abyssinica. Vernonia lasiopus  and  Uvariodendron anisatum  were the least active extracts. Susceptibility against  E. coli  and  C. albicans  was significantly comparable to benzathine penicillin and streptomycin.   Conclusion:  The type of ailments the plants are claimed to treat can be attributed to the presence of various classes of phytochemicals. In conclusion, the plants evaluated were found to be active against the microorganisms tested.

【 授权许可】

CC BY