Identification and Isolation of Caffeic, Chlorogenic and Ferulic Acids in Aerial Parts of Capparis spinosa wildly grown in Iraq

Iraqi Journal of Pharmaceutical Sciences

ARTICLE

Asmaa M. Hussein¹  Enas J. Kadum¹ 

[1] Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Baghdad

关键词: Capparis spinosa;    caffeic;    chlorogenic;    ferulic acids;    identification.;   

DOI  :  10.31351/vol29iss2pp185-193

学科分类：计算机网络和通讯

来源: College of Pharmacy University of Baghdad

【 摘 要 】

Capparis spinosa is one of the oldest genera grown in Iraqi territory with worldwide traditional medicinal uses beside the culinary uses. These uses were due to the presence of many phytochemicals including flavonoids and polyphenols. Among the reported polyphenolic acids were caffeic, chlorogenic and ferulic acids with wellknown and powerful antioxidant properties. The present work aimed to isolate and identify the presence of these polyphenolic acids in Iraqi Capparis spinosa (Iraqi caper) which is wildly grown in the middle areas following standard chromatographic procedures. Aerial parts of the plant (buds, berries and leaves) were extracted with hydroalcoholic solvent by maceration method. The extract was fractionated with chloroform, n-butanol and ethyl acetate. Thin layer chromatographic (TLC) techniques and high performance liquid chromatography (HPLC) analysis were performed to identify the presence of polyphenolic acids in the ethyl acetate fraction. The result obtained in this work showed the presence of these phenolic acids in the investigated extract. Chromatographic analysis revealed the presence of considerable amounts of these acids in ethyl acetate fraction when the separated spots were compared with Rf values and UV spectra of standards. Such data give a promising use of aerial parts of Iraqi caper for globally reported medicinal uses.

【 授权许可】

CC BY