Annual Seminar of Hellenic Osteoporosis Foundation: The role of mechanical factors on the musculoskeletal system

Journal of Frailty, Sarcopenia and Falls

ARTICLE

Christiana Zidrou

关键词: Bone modeling;    Remodeling;    Bone fragility;    Peak bone mass;    Fractures;   

DOI  :  10.22540/JFSF-01-058

学科分类：内科医学

来源: Hylonome Publications

【 摘 要 】

The cellular activities of bone modeling and remodeling determine the material composition and structure of bone. Bone modeling refers to the deposition of new bone without prior bone resorption. Bone remodeling is characterized by the appearance of focally and temporally distinct regions of resorption followed by bone formation that constitutes the basic multicellular units (BMUs).The purpose of bone modeling and remodeling during growth is to build peak bone strength. After the completion of growth, bone modeling continues in adulthood modestly to increase bone size further, whereas bone remodeling maintains bone strength by removal of microdamage.

【 授权许可】

CC BY-NC-SA