Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study

Basic and Clinical Neuroscience

ARTICLE

Talimkhani, Ailin¹  Abdollahi, Iraj²  Mohseni-Bandpei, Mohammad Ali³  Ehsani, Fatemeh⁴  Khalili, Sanaz⁵  Jaberzadeh, Shapour⁶ 

[1] Department of Physical Therapy, School of Rehabilitation Sciences, Hamadan University of Medical Sciences;Department of Physical Therapy, University of Social Welfare and Rehabilitation Sciences;Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences;Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences;Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences;Non-invasive Brain Stimulation & Neuroplasticity Laboratory, Department of Physiotherapy, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University

关键词: Transcranial direct current stimulation;    Primary motor cortex;    Dorsolateral prefrontal cortex;    Learning;    Motor skills;   

DOI  :  10.32598/bcn.9.10.350

来源: Iran University of Medical Sciences

【 摘 要 】

Introduction: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects of a-tDCSUHCDS and conventional M1 a-tDCS on the extent and durability of the motor sequence acquisition in healthy individuals. Methods: In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions. Results: Data analysis revealed that all groups exhibited the improved trend over the training course (P0.05), while a significant improvement was observed between experimental and sham group at the retention time (P0.05). Conclusion: These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field.

【 授权许可】

Unknown